Effectiveness of Fogged Disinfectants Against Norovirus on Challenging Surfaces: A Study of ClO2 and H2O2

The article titled “Virucidal Activity of Fogged Chlorine Dioxide- and Hydrogen Peroxide-Based Disinfectants against Human Norovirus and Its Surrogate, Feline Calicivirus, on Hard-to-Reach Surfaces” focuses on evaluating the effectiveness of fogged disinfectants in inactivating human Norovirus (NoV) and its surrogate, Feline Calicivirus (FCV), on surfaces that are difficult to clean.

Key Points of the Study:

  1. Background: Human Norovirus is a leading cause of acute gastroenteritis and is known for its environmental stability and resistance to common sanitizers and disinfectants. This makes it challenging to control its spread, especially in environments with frequent human contact.
  2. Disinfectants Used: The study used two strong oxidizing agents, Chlorine Dioxide (ClO2) and Hydrogen Peroxide (H2O2), delivered in gaseous form. These agents are known for their broad antimicrobial activity and are more effective in gaseous form than in liquid form.
  3. Methodology: The study involved using a fogging device to deliver these disinfectants in a controlled laboratory setting. The effectiveness of the disinfectants was tested against two human NoV outbreak strains (GI.6 and GII.4) and the cultivable surrogate FCV on stainless steel coupons.
  4. Results: The study found that both ClO2- and H2O2-based disinfectants were effective in reducing the viral load of human NoV and FCV. The fogging method allowed the disinfectants to reach and inactivate viruses on hard-to-reach surfaces.
  5. Conclusion: The research provides evidence of the efficacy of fogged disinfectants in inactivating human NoV in enclosed areas, suggesting their potential use in environments prone to NoV outbreaks.

This study highlights the potential of using fogged ClO2 and H2O2 as effective methods for disinfecting surfaces contaminated with human Norovirus, especially in environments where manual cleaning is challenging.

https://pubmed.ncbi.nlm.nih.gov/28642746/

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